Selko AOmix

Oxidative stress in cattle can cause various health problems, including reduced growth, immune function, and reproductive performance. To mitigate oxidative stress in cattle, it is important to provide a balanced diet with adequate levels of antioxidants. The effectiveness of antioxidants depends on factors such as their bioavailability and solubility. To address these concerns, specially formulated alternatives to vitamin E for cattle, such as Selko AOmix, have been developed. These alternatives provide optimal digestibility and cover the complete water-to-fat-soluble range, ensuring the delivery of antioxidants to every part of the cattle's cells.Crucial factors in antioxidant effectivenessGood bioavailability for optimal absorption: if the supplement is not well-digested, fewer antioxidants are made available. The bioavailability of antioxidants depends on the absorption and the distribution in the cells.Another factor in an antioxidant’s effectiveness is its water vs. fat solubility, which can vary widely. Solubility is what determines where antioxidants are distributed in the body. Vitamin E for cattle, for instance, mainly delivers its antioxidant effect at the cell membrane, and has less impact on the internal or external cell environment (Figure 1).Ruminants and monogastrics have different digestive systems. Therefore, the antioxidants offered to them differ in bioavailability. In ruminants, bioavailability is directly linked to the polyphenol’s susceptibility to fermentation in the rumen, the type of fermentation products produced, and the bioavailability of bypass polyphenols of polyphenol fermentation products. Based on that knowledge, Selko formulated ruminant specific alternatives to partially replace vitamin E for cattle. Plant extracts were selected which either contain bypass polyphenols or which are fermented into potent and bioavailable polyphenols. The resulting product is Selko AOmix and is capable of substituting and/or complementing the antioxidant protection that most cattle currently get from Vitamin E supplemented above requirements (Figure 2).

Product application

Oxidative stress in cattle can cause various health problems, including reduced growth, immune function, and reproductive performance. To mitigate oxidative stress in cattle, it is important to provide a balanced diet with adequate levels of antioxidants. The effectiveness of antioxidants depends on factors such as their bioavailability and solubility. To address these concerns, specially formulated alternatives to vitamin E for cattle, such as Selko AOmix, have been developed. These alternatives provide optimal digestibility and cover the complete water-to-fat-soluble range, ensuring the delivery of antioxidants to every part of the cattle's cells. Crucial factors in antioxidant effectiveness Good bioavailability for optimal absorption: if the supplement is not well-digested, fewer antioxidants are made available. The bioavailability of antioxidants depends on the absorption and the distribution in the cells. Another factor in an antioxidant’s effectiveness is its water vs. fat solubility, which can vary widely. Solubility is what determines where antioxidants are distributed in the body. Vitamin E for cattle, for instance, mainly delivers its antioxidant effect at the cell membrane, and has less impact on the internal or external cell environment (Figure 1). Ruminants and monogastrics have different digestive systems. Therefore, the antioxidants offered to them differ in bioavailability. In ruminants, bioavailability is directly linked to the polyphenol’s susceptibility to fermentation in the rumen, the type of fermentation products produced, and the bioavailability of bypass polyphenols of polyphenol fermentation products. Based on that knowledge, Selko formulated ruminant specific alternatives to partially replace vitamin E for cattle. Plant extracts were selected which either contain bypass polyphenols or which are fermented into potent and bioavailable polyphenols. The resulting product is Selko AOmix and is capable of substituting and/or complementing the antioxidant protection that most cattle currently get from Vitamin E supplemented above requirements (Figure 2).

Benefits

  • mitigates oxidative stress, reducing the risk of associated health problems.
  • offers a cost-effective alternative to vitamin E supplementation.
  • enhances reproductive performance and overall herd productivity.

Specifications

  • The natural antioxidants in the specially formulated Selko AOmix blend has not only been selected for ideal digestibility, it also covers the complete water-to-fat-soluble range to ensure optimal antioxidant activity in every part of the cell.

Selko AOmix

Invest in a healthier herd and more profitable operation today!

  • Oxidative stress in beef cattle can have a negative effect on health and growth performance. Feeding adequate levels of antioxidants can mitigate oxidative stress in beef cattle. With the recent sharp price increase of vitamin E, Selko AOmix provides a cost-effective and efficient alternative.

    Selko AOmix is the innovative, economical choice for beef farmers looking to effectively manage oxidative stress without depending solely on vitamin E.

    • Mitigates oxidative stress, reducing the risk of associated health problems.
    • Offers a cost-effective alternative to vitamin E supplementation.
    • Enhances reproductive performance and overall herd productivity.
    By partially replacing costly vitamin E, Selko AOmix delivers significant savings on feed costs—without compromising performance. Contact us today to find out how much money you can save by reducing the cost of your feed with Selko AOmix!
     
     
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  • The role of Selko AOmix in mitigating oxidative stress

    Beef cattle suffering from oxidative stress can have various problems, including reduced average daily gain and immune function. Beef in cow-calf operations can suffer from poor reproductive performance as a result of oxidative stress. Oxidative stress in beef cattle can be mittigated with a balanced diet containing adequate levels of antioxidants. Factors such as their bioavailability and solubility can impact effectiveness of antioxidants. To address concerns about bioavailability of antioxidants in beef cattle, specially formulated alternatives to vitamin E, such as Selko AOmix, have been developed for cattle. These alternatives provide optimal digestibility and cover the complete water-to-fat-soluble range. This ensures antioxidants are delivereds to every part of the beef cattle's cells.

    Crucial factors in antioxidant effectiveness in beef cattle

    • If the antioxidant in the supplement for beef cattle is not well-digested, fewer antioxidants become available for absorbtion by the animal. Absorption and the distribution into the cells are important factors influencing bioavailability of antioxidants in beef cattle.
    • Another factor that impacts effectiveness of an antioxidant for beef cattle is its water vs. fat solubility, which can vary widely between antioxidant products for ruminants. Solubility of antioxidants for beef cattle determines where they are distributed in the body. Vitamin E for instance mainly delivers its antioxidant effect at the cell membrane, and has less impact on the external or internal environment of the cell (see Figure 1).

    Ruminants have different digestive systems compared to monogastrics. As a result, antioxidants in their feed differ in bioavailability. Bioavailability of antioxidants in ruminants is directly linked to the polyphenol’s susceptibility to rumen fermentation, the type of fermentation products produced, and the bioavailability of bypass polyphenols of polyphenol fermentation products in beef cattle. For this reason, Selko has formulated ruminant specific alternatives to partially replace vitamin E for beef cattle. Plant extracts that are included in Selko AOmix for beef cattle either contain bypass polyphenols or polyphenols which are fermented into potent and bioavailable metabolites. Selko AOmix is therefore capable of substituting and/or complementing the antioxidant protection that most cattle currently get from Vitamin E supplementation above requirements (see Figure 2).

  • Selko AOmix is a cost-effective solution to partially replace vitamin E for beef cattle

    Administration

    The natural polyphenols in Selko AOmix are either water-soluble, biphasic (soluble in both water and fat) or fat-soluble, ensuring antioxidant support throughout the cellular environment.

    Selko AOmix can partially replace more expensive antioxidant ingredients in a feed formulation, such as vitamin E supplemented above beef cattle requirements. Due to the optimal bioavailability and distribution characteristics, polyphenols can support growth, fertility, and offspring antioxidant status. Adding Selko AO Mix to a feed formulation also improves stability of other vitamins.

    The advised Vitamin E Level in combination with feeding Selko AO Mix:

        Current Vitamin E Vitamin E New AO Mix R
    Receiving cattle IU/day 225 100 125
    Finishing cattle IU/day 500 240 360
    Growing cattle IU/kg DMI 20 15 5

     

  • Reach out to your local Selko nutritionist for free expert advice

    Thank you for contacting us. Your request for expert advice or customized product quote has been successfully submitted. In the meantime, we invite you to explore more about our innovative solutions on our website. Or you can discover best practices for cattle farming here .

Features

The natural antioxidants in Selko AOmix for beef have been selected for ideal digestibility and cover the complete water-to-fat-soluble range, ensuring optimal delivery of antioxidant activity in every part of the cell.

Benefits

Damaging effects of free radicals are mitigated by the antioxidants in Selko AOmix. Feeding Selko AOmix to beef cattle can improve performance under challenging conditions such as transition into the feedlot or periods of heat stress. Selko AOmix can reduce costs of a feed formulation for beef cattle by replacing more expensive vitamin E in case levels that are fed exceed NASEM recommendations for vitamin E levels fed to beef cattle for antioxidant purposes.

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    Improved performance with a sustainability advantage!
    GFLI Additives explained

    Discover how Selko IntelliBond has been scientifically assessed and became the first branded trace mineral in the GFLI database, setting new sustainability standards in animal nutrition. Watch the full webinar recordings online now!

     

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Polyphenols: a cost-effective solution to partially replace vitamin E

Discover the hidden threat of oxidative stress, a natural byproduct of metabolism, and how it affects your cattle's well-being. Download our product brochure to find innovative solutions to protect your herd from oxidative stress, ensuring their vitality even in challenging conditions like heat stress, high-concentrate diets, and health issues. Safeguard your cattle's health with Selko's proven solutions.

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Selko AOmix

Invest in a healthier herd and more profitable operation today!

Oxidative stress in dairy cattle can lead to various health issues and negatively impact reproduction, reducing overall herd performance. Feeding adequate levels of antioxidants is essential to mitigate these challenges. With the recent sharp price increase of vitamin E, Selko AOmix is the choice for dairy farmers looking to effectively manage oxidative stress without depending solely on vitamin E as it:

The role of Selko AOmix in combating oxidative stress

Figure 1. Antioxidants in Selko AOmix function throughout the cell

Figure 2. In-vitro assessment of antioxidative equivalence of Selko AOmix vs. synthetic vitamin E-50 using the KRL method (kit radicaux libres), showing that Selko AOmix has 5 times higher antioxidative capacity per weight unit.

Oxidative stress in cattle can cause various health problems, including reduced growth, immune function, and reproductive performance. To mitigate oxidative stress in cattle, it is important to provide a balanced diet with adequate levels of antioxidants. The effectiveness of antioxidants depends on factors such as their bioavailability and solubility. To address these concerns, specially formulated alternatives to vitamin E for cattle, such as Selko AOmix, have been developed. These alternatives provide optimal digestibility and cover the complete water-to-fat-soluble range, ensuring the delivery of antioxidants to every part of the cattle's cells.

Crucial factors in antioxidant effectiveness

  • Good bioavailability for optimal absorption: if the supplement is not well-digested, fewer antioxidants are made available. The bioavailability of antioxidants depends on the absorption and the distribution in the cells.
  • Another factor in an antioxidant’s effectiveness is its water vs. fat solubility, which can vary widely. Solubility is what determines where antioxidants are distributed in the body. Vitamin E for cattle, for instance, mainly delivers its antioxidant effect at the cell membrane, and has less impact on the internal or external cell environment (Figure 1).

Ruminants and monogastrics have different digestive systems. Therefore, the antioxidants offered to them differ in bioavailability. In ruminants, bioavailability is directly linked to the polyphenol’s susceptibility to fermentation in the rumen, the type of fermentation products produced, and the bioavailability of bypass polyphenols of polyphenol fermentation products. Based on that knowledge, Selko formulated ruminant specific alternatives to partially replace vitamin E for cattle. Plant extracts were selected which either contain bypass polyphenols or which are fermented into potent and bioavailable polyphenols. The resulting product is Selko AOmix and is capable of substituting and/or complementing the antioxidant protection that most cattle currently get from Vitamin E supplemented above requirements (Figure 2).

Administration

The natural polyphenols in Selko AOmix range from water-soluble to biphasic (soluble in both water and fat) to fat-soluble, ensuring antioxidant support throughout the cellular environment.

In a feed formulation, Selko AOmix can partially replace more expensive antioxidant ingredients such as cattle vitamin E supplemented above requirements. Due to the optimal bioavailability and distribution characteristics, polyphenols can support the immune system, fertility, and offspring antioxidant status.

Typical Vitamin E levels in practice. Vitamin E requirement + antioxidant function Minimum vitamin E requirement NASEM Amount of replaceable vitamin E for antioxidant purpose Vitamin E antioxidant function replacement with Selko AOmix*
Calculated with a BW of 650kg IU/day
Dry cows 2100 1100 1000 250
Prepartum cows within 3 weeks of calving* 3000 2000 1000 250
Lactating dairy cows and heifer 1100 550 450 113
*1 unit of Selko AOmix for ruminants (commercial name:
Selko AOmix R) can replace 4 units of synthetic vitamin E-50

Reach out to your local Selko nutritionist for free expert advice

Thank you for contacting us. Your request for expert advice or customized product quote has been successfully submitted. In the meantime, we invite you to explore more about our innovative solutions on our website. Or you can discover best practices for cattle farming here .

Features

The natural antioxidants in the specially formulated Selko AOmix blend has not only been selected for ideal digestibility, it also covers the complete water-to-fat-soluble range to ensure optimal antioxidant activity in every part of the cell.

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Hydroxy trace minerals improve milk production, health & fertility

Several scientific trials have proven the effects of Selko Intellibond. Prof. Dr. Santos at the University of Florida has again shown great results of our Hydroxy Trace Mineral mixture for cows. Watch the videos from the latest webinar and discover how Hydroxy Trace Minerals like Selko Intellibond can increase colostrum production with 1.5 kg (3.3 lbs) per cow per day and 1.4 kg ECM (3 lbs) per cow per day throughout the first 105 lactation days.

Benefits

Antioxidants in Selko AOmix mitigate the damaging effects of free radicals. Thereby supporting performance under challenging conditions like heat stress and the immune system and general health status. Selko AOmix can save costs by replacing the more expensive vitamin E levels exceeding NASEM recommendations (metabolic requirements) for antioxidant purposes.